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Tuesday, March 2, 2010
Radiographic Signs of Bone Destruction in the Arthritic Temporomandibular Joint
To investigate the progression of radiographic changes of the temporomandibular joint (TMJ) with the reference to plasma levels of interleukin-1B (IL-1B), C-reactive protien (CRP) and disease duration.
Twenty-one patients with chronic inflammatory joint disease and TMJ involvement were included. Individualized tomography of the TMJ was performed twice with an interval of at least 12 months.
Significant progression of the overall grade of radiographic changes occurred during the observation period, whereas erosions showed great interindividual variability. Progression of TMJ bone loss was correlated to raised levels of CRP and, in patients with a diagnosis of rheumatoid arthritis, or with a shorter duration, also to a plasma IL. Progression of an overall grade of radiographic changes in the TMJ occurs in patients with chronic inflammatory joint disease. Raised levels of serum CRP are associated with progression of TMJ bone lpss.
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