Self-Administration of Sphenopalatine Ganglion (SPG) Block at Home for Acute Migraine

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Posted: July 1, 2025

There is a recently published article on Self-Administration of SPG Blocks for acute Migraine at home.  The Abstract is at the bottom of this post.
The following is from AI:  
Self-administered sphenopalatine ganglion (SPG) blocks, often associated with professionals like Dr. Shapira, are discussed as a potential treatment option for headaches, including migraines and cluster headaches. 

What is a Self-Administered SPG Block? It involves the transnasal application of a local anesthetic to the area of the sphenopalatine ganglion (SPG). The SPG is a collection of nerves located in the pterygopalatine fossa, with connections to various parts of the head and face. Dr. Shapira has been teaching patients how to self-administer these blocks since the 1980s.

The preferred method for self-administration involves using cotton-tipped catheters and a 2% lidocaine solution.  How it May Work: The anesthetic is thought to block sensory fibers associated with pain perception and potentially influence the autonomic nervous system, which is involved in headache pathophysiology. Some research suggests the effect might be more diffuse, blocking trigeminal nerve afferents in the nasal mucosa, rather than just the SPG itself. 

Potential Benefits: Pain relief: Can provide rapid relief for migraines and cluster headaches.

Preventive potential: Some patients utilize self-administered SPG blocks prophylactically to prevent headache onset.

Cost-effective: Self-administered blocks are considerably less expensive than office-based or emergency room treatments. Improved patient control: Allows patients to manage their pain at home and reduce dependence on other medications. 

Regarding Cluster Headaches: SPG blocks, including self-administered ones, are considered for cluster headaches. Evidence supporting SPG blocks is stronger for cluster headaches compared to other headache disorders. In one case series, self-administered SPG blocks with lidocaine ended a cluster cycle early for one individual, although two others did not benefit in treating acute attacks. 

Important Considerations: Technique: Proper training is crucial for safe and effective self-administration. Safety: While generally safe, there's a potential for minor side effects like throat numbness. Consult a professional: It is important to discuss self-administered SPG blocks with your doctor to determine if it's an appropriate treatment option for you. 

In summary, self-administered SPG blocks are a potential adjunctive therapy for migraines and cluster headaches, offering the advantages of rapid relief, potential prevention, cost-effectiveness, and greater patient autonomy. However, it's essential to receive proper training and work closely with a healthcare professional. 

Dr Shapira has a dedicated site on Sphenopalatine Ganglion Blocks,

www.Sphenopalatineganglionblocks.com

Office website:   WWW.ThinkBetterLife.com


Abstract below:

Sphenopalatine ganglion (SPG) blocks: Evidence and implementation for acute migraine treatment in the primary care setting

 

Abstract

Background:

Sphenopalatine ganglion (SPG) blocks may be effective and affordable treatments for acute migraine but are rarely used in the primary care setting, making them inaccessible treatment for those suffering from migraine.

Objective:

To outline evidence for the use of SPG block in the treatment of acute migraine. To determine the feasibility and effectiveness of primary care in-office and at-home SPG block administration.

Methods:

A retrospective chart review of patients receiving in-office or at-home SPG block to treat acute migraine was completed. Pre- and post-treatment pain measurements were the primary outcome, along with patient-reported adverse effects.

Results:

Results from this study revealed that 87% of SPG block administrations (via catheter and atomizer) resulted in pain relief with minimal adverse effects. Methods and materials for catheter and atomizer administration of SPG blocks are outlined, in addition to tips for integrating this service into primary care practices.

Conclusions:

This study showed that SPG blocks may be administered effectively in primary care settings or at home with proper patient education and are an effective treatment modality to decrease pain associated with acute migraine.

Keywords: Migraine, headache, primary care, nerve block